Why Angina in Aortic Stenosis With Normal Coronary Arteriograms?

Why angina in aortic stenosis with normal coronary arteriograms?

Hypertrophy is considered one of the major mechanisms of the myocardium for adapting to hemodynamic overload. More muscle mass provides more contractile elements for generating the extra work required by the overload. In pressure overload of aortic valve stenosis, concentric left ventricular hypertrophy (LVH) normalizes wall stress, a key determinant of ejection performance.1 Afterload is often...

Variant Angina of Prinzmetal with Normal Coronary Arteriograms

Variant angina of Prinzmetal has been generally presumed to be caused by a significant focal obstruction in a single major coronary artery which should be an ideal lesion for aortocoronary saphenous vein bypass graft. Recognition of this clinical syndrome would then be of particular diagnostic and therapeutic importance if such a consistent association can be demonstrated. Of five patients with...

Angina with normal coronary arteriograms. Value of coronary sinus lactate estimation in diagnosis and treatment.

Aortic stenosis and angina with normal coronary arteries: the role of coronary flow abnormalities.

Angina is a common symptom among patients with significant aortic valve stenosis. The incidence of between 60% and 80% is notably higher than that observed in other valve diseases.1 2 In addition, a considerable proportion of patients with angina and aortic stenosis are found to have normal coronary arteries at angiography despite having objective evidence of myocardial ischaemia on electrocard...

Acute coronary insufficiency with normal coronary arteriograms.

Two patients presenting with apparent symptomatic and electrocardiographic evidence of acute coronary insufficiency and found to have normal coronary arteriograms are documented. The patients remain symptom free at follow-up 9 and 14 months later although one requires 160 mg propranolol daily. The electrocardiographic, myocardial metabolic and haemodynamic data in 413 patients with angina and n...